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The liver stores 3 to 5 years worth of b12 under normal circumstances
Semaglutide, marketed as Ozempic, Wegovy, and Rybelsus, has transformed treatment for type 2 diabetes and obesity
The averages you see in headlines reflect long-term results at higher dosesalongside lifestyle changesnot instant shifts in the first few weeks
Cases of monotherapy and polytherapy with GLP-1 RAs
Eli Lillys GLP-1 offering, tirzepatide, launched shortly after (as Mounjaro for T2D in 2022 and Zepbound for obesity in 2023), demonstrated greater HbA1c reduction and up to a 20% placebo-adjusted weight loss
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